Delivering Sleep Solutions

Sleep to Live Institute researches and develops solutions that help people achieve quality sleep in better quantities. We conduct research to solve current issues that affect our ability to achieve healthy sleep. Renowned sleep experts and members of the Sleep to Live Institute’s Sleep and Wellness Boards, Andrew Krystal, M.D., and Jack Edinger, M.D.,  of Duke University’s Sleep Disorders Center, completed a study with RTI international that reveals that sleep surfaces do matter.

View Sleep Research:

Hogan, S.O., Edinger, J.D., Bieler, G.S., & Krystal, A.D. (August 2011). Choosing the Best Mattress: An Experiment in Testing Whether Individuals Choose a Bed That Leads to Improved Sleep RTI Press. RTI Press Publication No. RR-0016-1108. READ

Krystal, A. D., Edinger, J. D., Bieler, G. S., Mladsi, S. W., and Hogan, S. O. (2011). Choosing a Mattress: Using Actigraphy and Diary Reports to Identify a Mattress That Provides Best Sleep. RTI Press publication No. RR-0015-1102. LINK
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Ensor J, Oexman R, Scott D, Carrier J, Davis J. Evaluation of a custom fit sleep surface using objective and subjective measures of sleep quality. 2008. Submitted for publication.
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Van Dongen HPA, Maislin G, Mullington JM, Dinges DF. The cumulative cost of additional wakefulness: dose-response effects on neurobehavioral functions and sleep physiology from chronic sleep restriction and total sleep deprivation. Sleep 2003; 2: 117-126.
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Dawson D, Reid K. Fatigue, alcohol and performance impairment. Nature 1997; 388: 235.
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Williamson AM, Feyer AM. Moderate sleep deprivation produces impairments in cognitive and motor performance equivalent to legally prescribed levels of alcohol intoxication. Ocuup Environ Med 2000; 47: 649-655.
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Spiegel K, Tasali E, Penev P, Van Cauter E. Brief communication: Sleep Curtailment in healthy young men is associated with decreased leptin levels, elevated ghrelin levels, and increased hunger and appetite. Ann Intern Med 2004; 141(11): 846-50.
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Van Cauter E, Knutson K, Leproult R, Spiegel K. The impact of sleep deprivation on hormones and metabolism. Medscape Neurology & Neurosurgery 2005; 7(1).
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Lorenzo I, Ramos J, Arce C, Guevara MA, Corsi-Cabrera M. Effect of total sleep deprivation on reaction time and waking EEG activity in man. Sleep 1995; 18(5): 346-354.
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Pilcher JJ, Huffcutt AI. Effects of sleep deprivation on performance: A meta-analysis. Sleep 1996; 19(4): 318-326.
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Glenville M, Broughton R, Wing AM, Wilkinson RT. Effects of sleep deprivation on short duration performance measures compared to the Wilkinson auditory vigilance task. Sleep 1973; 1(2): 169-176.
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Haack M, Sanchez E, Mullington J. Elevated inflammatory markers in response to prolonged sleep restriction are associated with increased pain experience in healthy volunteers. Sleep 2007; 30(9): 1145-1152.
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MedHeadlines. Immune system most active during sleep. 2008.
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Gangwisch JE, Malaspina D, Boden-Albala B, Heymsfield SB. Inadequate sleep as a risk factor for obesity: analyses of the NHANES I. Sleep 2005; 28(10): 1289-1296.
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Vgontzas AN, Liao D, Bixler EO, Chrousos GP, Vela-Bueno A. Insomnia with objective short sleep duration is associated with a high risk for hypertension. Sleep 2009; 32(4): 491-497.
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Robillard R, Lanfranchi PA, Prince F, Filipini D, Carrier J. Sleep deprivation increases blood pressure in healthy normotensive elderly and attenuates the blood pressure response to orthostatic challenge. Sleep 2011; 34(3): 335-339.
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Laino C. Sleep deprivation linked to weight gain. Medscape Medical News 2006. Based on selected sessions at the American Thoracic Society 2006 International Conference.
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Kakizaki M, Kuriyama S, Sone T, Ohmori-Matsuda K, Hozawa A, Nakaya N, et al. Sleep duration and the risk of breast cancer: the Ohsaki Cohort Study. Br J Cancer 2008; 99(9): 1502-5.
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Nagai M, Hoshide S, Kario K. Sleep duration as a risk factor for cardiovascular disease- a review of recent literature. Current Cardiology Reviews 2010; 6: 54-61.
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Spiegel K, Sheridan J, Van Cauter E. Letter on the effect of sleep deprivation on response to immunization. JAMA 2002; 288(12): 1471-1472.
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Dimitrov S, Lnage T, Nohroudi K, Born J. Number and function of circulating human antigen presenting cells regulated by sleep. Sleep 2007; 30(4): 401-411.
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Cohen S, Doyl WJ, Alper CM, Janicki-Deverts D, Turner RB. Sleep habits and susceptibility to the common cold. Arch Intern Med 2009; 169(1): 62-67.
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